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Study population We initially included 10,585,844 Korean adults aged 20 years or older who had participated in NHSP in 2009 from the NHIS database of the entire Korean population

197 For therapeutic purposes, the specificity of the potent target sites would be the critical prerequisite for the development of new inhibitors of NLRP3 inflammasome

Ethics approval A study did not require ethics approval

Four studies demonstrated improvements that met or exceeded the lower bound for clinical relevance

ChIP assay The relevance of ER or ERR transcription factors to the target genes of interest was first queried on their respective ENCODE and ChEA datasets located on Harmonizome 160