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This process resulted in increased subchondral bone stiffness, which subsequently altered the local biomechanical environment of the joint, exacerbating cartilage damage and accelerating the progression of OA (Sowers et al., 1996

A healthy dose of 5000-8000 IU per day of vitamin D, targeting a blood level of 50-80 ng/mL, may be the best way to ensure you safely get all of the optimal health benefits of the sunshine vitamin

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Hence, larger amounts of ROS are generated in the mitochondria of these neuronal structures