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In cardiomyocytes exposed to hypoxia, silencing of G6PD prevented antiapoptotic signaling in response to benfotiamine, indicating that the beneficial effects of benfotiamine on cardiomyocytes may be due to increased activation of G6PD

10.1097/MOP.0000000000000278 [DOI] [PMC free article] [PubMed] [Google Scholar] 14

Prion Protein Regulates Glutathione Metabolism and Neural Glutamate and Cysteine Uptake via Excitatory Amino Acid Transporter 3. Journal of Neurochemistry 133: 558571

FDA lists wound healing and inflammatory conditions as evaluated uses
