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Description
A bridging [4Fe4S] cluster and nucleotide binding are essential for function of the Cfd1Nbp35 complex as a scaffold in ironsulfur protein maturation
Kumar and K

These studies directly attribute the cytotoxicity of high-risk variants to their cation pore function

This process leads to the accumulation of cholesterol in the endoplasmic reticulum and increased production of 24-hydroxycholesterol (24HC)

Cancer Res 67(24):11687-11695, 2007

Ranran GAO, Zhen S, Menghui L, et al
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