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Upon T-cell receptor (TCR) activation, mitochondrial oxidative phosphorylation (OXPHOS) and NOXs are upregulated, leading to increased ROS production, which fuels T-cell proliferation and interleukin (IL) secretion

Hence, while the effects of novel inhibitors of methionine biosynthesis (sulfate reduction), or specific fungal methyltransferases, could be minimal in mammals, this could allow selective fungal inhibition

Cante B, Monsarrat B, Lazorthes Y et al

Kinetic and pharmacological properties of GABA(A) receptors in single thalamic neurons and GABA(A) subunit expression

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Serotonin transporter gene polymorphisms and hyperserotonemia in autistic disorder
