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Berdyski M, Miszta P, Safranow K, Andersen PM, Morita M, Filipek S, ekanowski C, Kuma-Kozakiewicz M

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Fishers exact test showed significant overlap between these gene sets ( p = 3.2 10 246 ) and all 89 overlapping genes were altered in the same direction

People who do not have adequate vitamin D levels might be at increased risk of infections and autoimmune diseases, such as rheumatoid arthritis, type 1 diabetes, and inflammatory bowel disease

7 Changes in the brain cytoplasmic [NAD + ]/[NADH] and [NADPH]/[NADP + ] with aging are rodent strain and species specific Through measuring the metabolome of young and aged C57BL/6J mouse brains, the lactate/pyruvate, a proxy for the cytoplasmic [NADH]/[NAD + ], was found to increase by 34%52% with aging, indicating a cytoplasmic reductive shift (Dong and Brewer, 2019), opposite to the oxidation of mitochondrial [NADH] that was found to occur in aged neurons (Dong et al., 2019a)