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doi: 10.1053/j.gastro.2015.09.004 49 MitaMSatohMShimadaAOkajimaMAzumaSSuzukiJSet al

The Ca2+ binding ER membrane protein stromal interaction molecule 1 (STIM1) senses the Ca2+ store depletion and then oligomerizes and interacts with plasma membrane store-operated Ca2+ (SOC) channel Orai1, leading to Ca2+ influx 27
