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Of note, CTP:phosphocholine cytidylyltransferase (CCT), the rate-determining enzyme in de novo synthesis of PC, was less expressed in IECs from Apc +/Min /Stard7 IEC mice, possibly as a result of PC accumulation in the ER due to a defective transfer to mitochondria (Fig

Figure 4 Furthermore, anti-PD-L1 treatment reverses the immunosuppressive status of the TME and enhances specific T cell anti-tumor effects in murine models of cancer (142)

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