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Description
S2A, Fig
2014;4:e232
That 3-5mg shortfall means reduced appetite suppression, less metabolic benefit, and slower progress
Lets break down the likely culprits
Phenytoin is primarily metabolized by the hepatic cytochrome P450 enzyme CYP2C9 and to a lesser extent by CYP2C19 and is particularly susceptible to inhibitory drug interactions because it is subject to saturable metabolism
S2CID 31973969.
