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Common experiences after the first injection include: Mild soreness or redness at the injection site (usually resolves within 12 days) Slight improvement in energy levels or mood No immediate noticeable change (particularly common if deficiency is severe) Rarely, mild side effects such as headache or dizziness Some patients report their urine becoming brighter or more intensely coloured following injection, which occurs because excess B12 is excreted renally

Expiration time Many serums are yellow, but if your product takes on a brown or dark orange hue, its time to toss because its gone bad

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Above and beyond that would be capable of platelet-rich plasma

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PMID 16854231