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10.1186/1471-2377-9-S1-S2 132 StohsS

The mechanism of action of n-acetylcysteine in trichotillomania is believed to be the reduction of glutamate levels in the nucleus accumbens

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Considering that glutathione is involved in the elimination of harmful substances such as: alcohol, drugs, solvents, pesticides, heavy metals, and many other toxic xenobiotic products that induce a state of cellular stress [71], it is evident that glutathione homeostasis becomes more relevant, because cells require an antioxidant agent that either prevents or reduces this stress, whether by trapping, metabolizing or turning them into less toxic agents [71,101]

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2017;9:S84S91