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Over time, the retina accumulates lipofuscin, a byproduct of cellular metabolism that can hinder proper retinal function

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The long-term effects of re-established normoglycemia have been studied both in non-uremic patients receiving a pancreas transplant alone (PTA) and uremic patients given simultaneous pancreas and kidney transplant (SPK)

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Hence we used an alternative approach where we analyzed the oxidized protein derivatized with Au 15 SG 12 -Ao after subsequent degradation of the grafted NC and trypsin digestion, whereby the putative oxime bond between the aminooxy on the NC and carbonylated amino acids on the protein remained intact