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Parkinson disease epidemiology, pathology, genetics, and pathophysiology

Ca 2+ is a master regulator of eryptosis, mediating the Gardos effect-associated RBC dehydration and reduction of cell volume (cell shrinkage), calpain activation-mediated cytoskeleton remodeling (membrane blebbing), and PS externalization, which are major hallmarks of eryptosis

Importantly, the clinical translation of these technologies will depend not only on analytical performance and the generation of new knowledge, but also on cost-effectiveness, scalability, and compatibility with existing laboratory workflows

B12 maintains the myelin sheath around your nerves, which keeps signals moving fast and accurately between your brain and body

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JCI Insight 5 , e133282 (2020)