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Its high specificity is a key area of research interest, as it has been shown in preclinical models to induce a strong GH pulse without significantly impacting other hormones such as cortisol, prolactin, or aldosterone, and without the appetite-stimulating effects associated with ghrelin itself

Its hepatic production is upregulated via the IL-6/STAT3 signaling pathway, and it facilitates fibrosis by enhancing hepatic stellate cell activation [207]

2018 Jan;6(1):45-53

A previous publication has proved the intestinal protective effect of Lactobacillus acidophilus LB strain (LB) against MTX-induced intestinal injury

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