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Description
The FDA has approved one MSC-based product, Remestemcel-L from Mesoblast Corporation, for the treatment of steroid-refractory acute graft-versus-host disease (SR-aGVHD) utilizing allogeneic culture-expanded BM-MSCs 151,152
This Figure shows conversion of glutamine to glutamate by PAG, followed by a process similar to that occurring in the MAS, with the only exception that the glutamate molecule involved does not originate in the cytosol, but from PAG-activated de-amidation of glutamine in the intermembranaceus space of the mitochondrion
10.1007/s00586-008-0749-z
Three-dimensional localization of cortical electrodes in deep brain stimulation surgery from intraoperative fluoroscopy
(2020) the FSHD phenotype may be the cumulative result of extensive aberrant signalling across time [80] with unpredictable bursts of expression [81]
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