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2 Biological mechanisms of ferroptosis 2.1 Overview of ferroptosis Ferroptosis is a distinct type of programmed cell death, setting itself apart from conventional forms like apoptosis, necrosis, and autophagy

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We hypothesized that the Nrf2-driven increase in expression of Slc7a11 and Gclc , and higher levels of GSH in KPK cells may result in export of glutamate in exchange for import of cystine (Figure 2A)