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Direct Adrenergic Agonism: Ephedrine is also able to directly bind to multiple post-synaptic adrenergic receptor subtypes to initiate intracellular signaling cascades: : Activation of vascular smooth muscle 1 -Adrenergic Activation 1 -adrenergic receptors produces arterial and venous vasoconstriction, leading to an increase in systemic vascular resistance (SVR), diastolic blood pressure, and systolic blood pressure (Solanki et al, 2014)

DHAR breaks DHA to ascorbic acid, utilizing reduced GSH, which is critical for maintaining sufficient ascorbate levels

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PMID: 14722139 DOI: 10.1001/jama.291.2.182-a Shih ML et al (1994): Metabolite pharmacokinetics of soman, sarin and GF in rats and biological monitoring of exposure to toxic organophosphorus agents