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Analgesic and antidepressant effects of the clinical glutamate modulators acetyl-L-carnitine and ketamine

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Caution is advised when using both together

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All data were shown as mean Standard deviation (SD) and number (percent)

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Adv Robot 33(78):424438 Li X, Dai Q, Shi Z, Chen H, Hu Y, Wang X, Zhang X, Tian G (2019d) Clinical efficacy and safety of electroacupuncture in migraine treatment: a systematic review and network meta-analysis

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Acetate is the most abundant SCFA and is thought to have diverse beneficial effects on the body, including reducing inflammation, preventing the overgrowth of harmful bacteria, regulating pH, and improving gut barrier function

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The picture is further muddied by limitations in the studies, and different study designs, e.g., variations in patient populations, dosages, treatment durations, and outcomes, which make it impossible to synthesize a final answer to whether L-carnitine works

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