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Hence, we hypothesised that co-administration of physiologically relevant doses of EA might improve the responsiveness of EGFRm/T790M tumours to erlotinib in vivo

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Second, MSC function is largely dependent on culture conditions [6, 7]

doi:10.1038/nature09746

288 ROS reversibly oxidize TRX at the Cys32 and Cys35 residues, dissociating it from ASK1 (activation), which, in turn, activates JNK