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Following nebulization, the liposomes are largely retained in the lungs with the help of SPB, where they target tumor cells and release their therapeutic payload

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3.4 Macrophage polarization modulation by Se/LDH@PEG-M Emerging evidence underscores the critical association between OA progression and disrupted M1/M2 macrophage polarization within synovial tissues, where excessive ROS accumulation serves as a key driver of pro-inflammatory M1 phenotype dominance [44]

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