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10.1021/acscentsci.1c00866 276 Zanotto-FilhoA.BraganholE.KlafkeK.FigueirF.TerraS

doi: 10.1007/s11892-019-1173-y

PBT2 acts by modulating metalprotein interaction networks, thereby restoring ironcopper balance in the brain and indirectly reducing A deposition, offering dual-target therapeutic potential (Chen L

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However, when these defenses are compromised, LPO can become more prominent or even the dominant mechanism of cell death