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The credibility signal is academic: its products are cited across many peer-reviewed papers

Frey II, a pioneer in intranasal central nervous system (CNS) delivery and adjunct professor at the University of Minnesota, explained it perfectly: We proved you could noninvasively deliver stem cells to the brain from the nose

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Intramuscular injection is the recommended and safer route

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If certain activities trigger piriformis syndrome for example, running or biking find another way to exercise, at least for a few days