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They observed that compared to the controls, the total antioxidant status was decreased, total oxidant status was increased, and markers of apoptosislike PARP-1 and Caspase-3 were elevated in the CBZ-treated group, leading to their conclusion that renal toxicity due to CBZ treatment occurs through oxidative stress-mediated apoptosis 19

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Jabre, P

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In the latest international pooled analysis, the adverse associations of TMAO with certain cardiometabolic biomarkers have been elucidated, and the mechanisms of action, independent of renal function, warrant further investigation ( Publisher's Note All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

[DOI] [PubMed] [Google Scholar] 162.Barera G, Mora S, Brambilla P, Ricotti A, Menni L, Beccio S, Bianchi C