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10.1016/j.clcc.2018.02.013 Clin
Familial PD caused by a mutation in glucocerebrosidase ( GBA1 ) leads to the metabolic dysregulation of the important bioactive lipid ceramide and imbalance of its intermediate glucosylceramide (Plotegher et al., 2019)
Both the treatment and placebo groups showed significant symptomatic improvement
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