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This recommendation stems from the risk of analytical errors influencing clinical decisions ( 2 )

Standardization of biomarker assays across laboratories, cost-benefit analyses to justify widespread adoption, and large-scale, multi-center validation studies remain essential steps to ensure reliability, reproducibility, and clinical utility

Muthiah, Won-Mook Choi Current Hepatology Reports .2025;[Epub] CrossRef A greater frequency of circulating CCR7loPD-1hi follicular helper T cells indicates a durable clinical cure after Peg IFN- therapy in chronic hepatitis B patients Shan Ren, Xiao Lin, Wenjing Wang, Wang Xiaoxiao, Lina Ma, Yanhong Zheng, Sujun Zheng, Xinyue Chen Hepatology Communications .2025;[Epub] CrossRef Risk of Hepatocellular Carcinoma Decreases After Antiviral TherapyInduced HBsAg Seroclearance Han Ah