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First, LPS directly affects thyroid cells by increasing the expression of thyroid-stimulating hormone (TSH)-stimulated thyroglobulin (Tg) and NIS genes, which was demonstrated in a rat thyroid cell line (FRTL-5) (31, 33)

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For this reason, early identification may help clinicians define appropriate monitoring strategies and timely supportive interventions

The chemokine CXCL12 is a potent chemoattractant for lymphocytes and monocytes but not neutrophils (Bleul et al., 2004