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Genetic factors influence key clinical features of migraines, such as earlier onset age, higher frequency in male patients, and increased medication usage (Pelzer et al., 2019)

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Increased serotonin production may contribute to behavioral abnormalities, migraine, headaches, and changes in cerebral blood flow [2]

Journal of aging research

More so, it had been reported that L-citrulline regulates muscle protein synthesis via mechanisms of the mTOR pathway [7, 153] and S6K-1 phosphorylation in LPS-treated rats [148]

doi: 10.1210/er.2009-0041 4 GallandSGeorgesBLe BorgneFConductierGDiasJVDemarquoyJ