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246 , F334F342 (1984)

5 Conclusion Atopic dermatitis is a chronic inflammatory skin disorder characterized by disruptions in skin barrier integrity and immune dysregulation

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[DOI] [PubMed] [Google Scholar] Parthasarathy S

Other organs, including the retina, kidneys, gastrointestinal system, skin and lymphocytes, produce a modest amount of melatonin (42,43,45,47,48)

It achieves this function by upregulating the mitochondrial reductase FDX1, which promotes the reduction of Cu(II) to the more reactive and toxic Cu(I) and simultaneously depletes the primary antioxidant and metal buffer, reduced glutathione (GSH)
