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Concurrently, excessive poly ADP-ribose (PAR) polymers generated by PARP-1 accumulate intracellularly, forming PAR signaling platforms that recruit pro-death factors like AIF [67]

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MAPKs are categorized into several different groups, among which c-Jun N-terminal kinases (JNKs) are clearly affected by ROS [66]

Maintaining optimal glutathione levels is vital for overall well-being, as low levels have been associated with cardiovascular diseases and neurodegenerative disorders

Assessment of Iodine Deficiency Disorders and Monitoring Their Elimination: A Guide for Programme Managers, 3rd ed (2007) World Health Organization: Geneva, Switzerland.[Available from: Food, Board N (2025) Institute of Medicine 2006 Dietary Reference Intakes