glutathione reductase deficiency anaemia The biological effects of glucose-6-phosphate dehydrogenase (G6PD) in Redox State of Glutathione and

Embodiment 40

ROS could inhibit macromolecules such as lipids, nucleic acids, and proteins (29, 30)

[DOI] Knudson D

By regulating oxidative stress responses, exercise can enhance the bodys antioxidant capacity, slow downing the progression of neurodegenerative changes (Xie et al., 2021)

ILC2-derived LIF licences progress from tissue to systemic immunity

But there is a grey/intermediary zone that exists (148-500 pmol/L ish), where patients may be deficient on a cellular level (in energy cycle and methylation) and wildly symptomatic including overt bilateral neurological symptoms, cognitive symptoms, severe fatigue (usually in the absence of anaemia) etc