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Addisons Disease (Hypoadrenocorticism) Diffuse pigmentation of the oral cavity and skin is an early and highly specific manifestation of Addisons disease, occurring in up to 92% of patients [8]

Therefore, checking for carnitine deficiency in cases of refractory PN cholestasis is highly recommended
A., Zagkos, L., Day, A
10.1161/JAHA.120.016441 20 YangY
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