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PMC 3062981

In a 2-year trial involving patients with type 2 diabetes mellitus (T2DM) and high cardiovascular risk, more events of diabetic retinopathy complications occurred in patients treated with semaglutide 0.5 and 1 mg once weekly injections (3%) compared to placebo (1.8%)

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Long-term considerations for semaglutide B12 therapy Semaglutide is not a short-term medication

The exact absorption rate is hard to predict, but this sustained release should help maintain steadier blood levels of B12

Patients can also be at risk for low levels of B12 if they are taking certain medications such as antacids or antihistamines, which can block the absorption of B12