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In another study, vitamin A deficiency was found to result in thickening of the cement, contraction of the periodontal ligament, irregularities in the periodontal ligament, thickening of the alveolar bone, and labial alveolar periosteum, and these results were shown to be reversible with replacement therapy [92]

PMID: 22420153

Collagen and Elastin Synthesis GHK-Cu activates dermal fibroblasts to increase production of type I and type III collagen and elastin

They demonstrated that human pancreatic tumor and stellate cells activate/process GSAO into its active metabolite and that GT activity positively correlates with GSAO-mediated proliferation arrest of co-cultured endothelial cells ( Figure 3B )