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At the time of writing (October 2024), the primary recommendation comes from ANZCAs Clinical Practice Recommendation On Periprocedural Use Of GLP-1/GIP Receptor Agonists
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GLP-1 receptors are also found in the hippocampus, a key structure for learning and memory
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The trials differed significantly in their design, including baseline patient characteristics (e.g., the REWIND trial included a majority of patients for primary prevention, whereas others focused on high-risk secondary prevention populations), follow-up duration, and specific drug properties, all of which likely contribute to the variable magnitude of benefit observed [63]
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