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EbertSWeigeltKWalczakYDrobnikWMauererRHumeDet alDocosahexaenoic acid attenuates microglial activation and delays early retinal degeneration

doi: 10.1038/s43587-023-00360-x

Interrogation of the mechanistic consequences of depleting its E1 subunit, 2-oxoglutarate dehydrogenase (OGDH), led us to identify a cancer-sustaining metabolic node that links KG flux through the tricarboxylic acid (TCA) cycle to de novo nucleotide production

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FIGURE 2 Figure 2B shows that EAR-20 produced a significant instantaneous potentiation (peak current) only for GluN1-GluN2A and GluN1-GluN2B with this rapid effect being more pronounced in GluN2B (15.68% 6.19% and 102.6% 24.02% for GluN2A and GluN2B

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