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10.1200/JCO.2016.34.15_suppl.8005 47

These different results could be accounted for by both the expression of NADPH oxidase induced by KRAS G12D overexpression, which leads to ROS generation, and an increase in NRF2-dependent ROS scavenging in cells expressing physiological levels of KRAS G12D

doi: 10.3389/fmolb.2022.917921

Although further multi-omics studies will certainly uncover more specific epigenetic profiles, a comprehensive genome-wide overview cannot be completed without in-depth functional analyses to reveal pathogenic mechanisms at the molecular level

Sorafenib can also be used in combination with various chemotherapy drugs, including paclitaxel, cisplatin, and 5- fluorouracil

Always check with the specific payer for requirements