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However, how these signaling molecules are released from the cells where they are synthesized so that they can act on their target receptors is poorly understood, although it seems likely that multiple cell type-specific mechanisms are involved

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[DOI] [PubMed] [Google Scholar] Rao E, Weiss B, Fukami M, Rump A, Niesler B, Mertz A, Muroya K, Binder G, Kirsch S, Winkelmann M, Nordsiek G, Heinrich U, Breuning MH, Ranke MB, Rosenthal A, Ogata T, Rappold GA

In pulmonary diseases, andrographolide has a large number of animal and cell experimental models for the treatment of inflammatory diseases, showing its important role in the treatment of pulmonary diseases