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this statement strongly suggested the importance of antitussive and mucoactive therapy in COPD patients
Curr Topics Dev Biol (2007) 79:3759

doi: 10.3390/life5041610
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As a pharmacological agent, papaverine is not exempt from adverse effects including endothelium damage, epileptic seizures, transient neurological dysfunction, and hemodynamic changes, among others (Dipp et al., 1999)

So I really walk people through that in the book
