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Ogose A, Hotta T, Morita T, Higuchi T, Umezu H, Imaizumi S, et al

Experimentally, haploinsufficiency of the nonhomologous end-joining DNA repair pathway in the context of Ink4a/Arf -deficient mice leads to the development of sarcoma with varied histology and karyotype

This mismatch suggests that P2X receptors functioning in MTNs possess unique subunit compositions or accessory factor dependencies, indicating the existence of MTN-specific purinergic regulatory mechanisms

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