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Considering the low l-serine levels in CSF and plasma, dietary l-serine supplementation has been tested as a therapeutic approach, with dietary l-serine supplementation ranging from 80 to 700 mg/(kgday) reported to improve biochemical and clinical outcomes in these patients (116)

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Acta Neuropathol 134:489506

10.3390/ijms22095010 30

Membranal expression of calreticulin induced by unfolded protein response in melanocytes: A mechanism underlying oxidative stress-induced autoimmunity in vitiligo

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