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The inhibitory effects of melittin and BV on c-Jun N-terminal kinases (JNK) signaling were observed at concentrations of 5 g/mL and within a range of 0.15 g/mL, respectively

E.KimM.GusevA.LoweJ

Affiliation: 1 Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA 2 Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA 3 Center for Microbiome & Human Health, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA Email: [email protected] ORCID: Affiliation: 4 Department of Neurology, Neurological Institute, Cleveland Clinic, Cleveland, OH 44195, USA ORCID: Affiliation: 1 Department of Cardiovascular and Metabolic Sciences, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA 2 Department of Molecular Medicine, Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH 44195, USA 3 Center for Microbiome & Human Health, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA 5 Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, Cleveland, OH 44195, USA Explor Med

The successful functionalization of SBA-15 with thiol and amine groups provides a suitable platform for further conjugation with SNCDs and FA

How it works: KPV is a tiny three-amino-acid fragment of alpha-MSH, a natural anti-inflammatory hormone

Encouraging advances made in the realm of redox biology have unveiled a host of complex inflammatory signaling mechanisms mediated by ROS, which may have profound implications for inflammatory lung diseases