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10.3389/fnagi.2020.580001 Front

Biochimica et Biophysica Acta (BBA)Molecular Cell Research

A suboptimal intake of the essential amino acids increases the body's need for the non-essential amino acids either through diet or supplementation

These effects compound over weeks of consistent supplementation rather than occurring acutely after a single dose.

This condition commonly involves three characteristic features: chronic mucocutaneous candidiasis (CMC), hypoparathyroidism, and adrenal gland insufficiency