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doi: 10.3389/fnmol.2018.00320 270 McKenzieBAMamikMKSaitoLBBoghozianRMonacoMCMajorEOet al

PT-141 is typically used on demand (taken before intended activity) with effects within 1, 2 hours

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Together, these mechanisms form a self-amplifying loop of neurotoxicity, highlighting the need for multi-targeted therapies to effectively protect and repair the ischemic brain
