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These results indicated that the SC-NEs with appropriate ligand density could achieve optimal cellular uptake, and neither too low nor too high a ratio of SC modification was not beneficial for the cellular uptake of SC-NEs

Diabetic and nondiabetic lumbosacral radiculoplexus neuropathies: new insights into pathophysiology and treatment

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Am J Cardiovasc Pathol 3(2):131142 Walter MF, Jacob RF, Jeffers B, Ghadanfar MM, Preston GM, Buch J, Mason RP (2004) Serum levels of thiobarbituric acid reactive substances predict cardiovascular events in patients with stable coronary artery disease: a longitudinal analysis of the PREVENT study

The critical factor is that loading usually takes at least 2-3 months, so this is best timed to coincide with the start of serious building in training load towards a goal