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For example, a mutation in the catalytic domain of Nox2 or in the domain responsible for interacting with the other NADPH subunits leads to a total loss of oxidative burst, whereas some mutations in the dehydrogenase domain have no effect on ROS production by phagocytes (Holland, 2013

Bayr, H

HAGR indexes genes related to aging and summarizes studies that document their functions

Eklof V, Van Guelpen B, Hultdin J, Johansson I, Hallmans G, Palmqvist R

mPFC is a key region involved in executive function and adaptive behavior and appears important for aspects of social cognition, including theory of mind(Zhang et al., 2021), all commonly different in autism

For the RRM1 knockdown condition, reverse transfection reagent was prepared on top of glass coverslips in six-well dishes using either non-targeting control siRNAs, or siRNA pools targeting human RRM1 , as described above