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In the vascular system, GH/IGF-1 receptors are widely expressed

Macrophages can also endocytose IgG-bound latent TGF- complexes that are secreted by plasma cells and then release active TGF- into the extracellular fluid

Third, a significant translational gap persists between preclinical efficacy and clinical application

In vivo diabetic wound healing of G/D-CuP Male C57BL/6 mice were fed with a high-sugar, high-fat diet for four weeks, followed by intraperitoneal injection of premade streptozotocin (STZ) solution at a dose of 50 mg kg 1 daily for one week