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Horowitz NH: On the evolution of biochemical syntheses

Arabidopsis has multiple NAD-MDH isoforms, including mitochondrial AtmtNAD-MDH1 and AtmtNAD-MDH2 (which function in the TCA cycle and photorespiration), three cytosolic MDHs (cyNAD-MDH13), and one plastidic MDH (plNAD-MDH), as well as two peroxisomal MDHs (pNAD-MDH12) involved in photorespiration (Selinski and Scheibe, 2019)

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They estimated that the number of segregating mtDNA units in PGCs was 200 and that the multiple cell divisions of the oogonia required to generate that large a number of primary oocytes were sufficient to account for the observed variance in heteroplasmy frequency of oocytes and offspring
