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Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA

This may be along with general COX 1 and COX 2 specificity (24), with the pyloric sphincter less sensitive to COX 2 and the lower esophageal sphincter more sensitive, but ultimately both affected by inhibition of both COX 1 and COX 2

This is why many people receive their vitamin B12 shots monthly