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Briefly, all pigs were injected with LPS (serotype O55:B5
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Mitochondrial dysfunction leads to the decrease of NAD + level, resulting in lysosomal acidification and impaired autophagy, and induces ferroptosis, involving the accumulation of iron in lysosomes and lipid peroxidation
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Seretny M, Currie GL, Sena ES, Ramnarine S, Grant R, MacLeod MR, et al
doi: 10.1038/s41467-020-15441-3
