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However, no improvement was observed in performance times, blood lactate, pH, or base excess, indicating no ergogenic benefit for short, high-intensity anaerobic swimming (Hou et al

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Study 1825: Virologically-suppressed adults with end stage renal disease (ESRD) receiving chronic hemodialysis In Study 1825, the efficacy and safety of GENVOYA once daily were evaluated in an open-label clinical trial of 55 virologically-suppressed (HIV-1 RNA less than 50 copies per mL for at least 6 months before switching to GENVOYA) HIV-1 infected subjects with ESRD (estimated creatinine clearance of less than 15 mL per minute by Cockcroft-Gault method) receiving chronic hemodialysis for at least 6 months [see Use in Specific Populations (8.6) and Clinical Pharmacology (12.3) ]

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Absorption of orally administered l-carnitine is very variable and ranges from 5 to 18% for pharmacological doses of up to 75% for dietary l-carnitine

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Physiol 291 , R1243R1255 (2006)

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